Simple sample size calculation for cluster-randomized trials | Zendy

Richard Hayes | Zendy; S. Bennett | Zendy

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Simple sample size calculation for cluster-randomized trials

Author(s) -

Richard Hayes,

S. Bennett

Publication year - 1999

Publication title -

international journal of epidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.406

H-Index - 208

eISSN - 1464-3685

pISSN - 0300-5771

DOI - 10.1093/ije/28.2.319

Subject(s) - sample size determination , cluster (spacecraft) , statistics , randomized controlled trial , tanzania , medicine , cluster randomised controlled trial , clinical trial , demography , mathematics , computer science , surgery , geography , environmental planning , sociology , programming language

Cluster-randomized trials, in which health interventions are allocated randomly to intact clusters or communities rather than to individual subjects, are increasingly being used to evaluate disease control strategies both in industrialized and in developing countries. Sample size computations for such trials need to take into account between-cluster variation, but field epidemiologists find it difficult to obtain simple guidance on such procedures.

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