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Research has produced conflicting findings about whether there is an excess of like-sexed pairs among concordant multiple sclerosis (MS) sibships. Although a positive correlation in onset age among sibling pairs overall has been reported, no data have been published describing age at onset correlations for like-sexed versus unlike-sexed pairs. The purpose of this study was to provide additional information on both issues.

Influence of Gender on Susceptibility to Multiple Sclerosis and Age of Onset in Concordant Sibships