In search of the best xenogeneic material for a paediatric conduit: an experimental study† | Zendy

I. Yu. Zhuravleva | Zendy; N. R. Nichay | Zendy; Yu.Yu. Kulyabin | Zendy; T.P. Timchenko | Zendy; Aleksandr A. Korobeinikov | Zendy; Yuliya F. Polienko | Zendy; S. S. Shatskaya | Zendy; Elena V. Kuznetsova | Zendy; A.V. Voitov | Zendy; Alexander BogachevProkophiev | Zendy; Alexander Karaskov | Zendy

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In search of the best xenogeneic material for a paediatric conduit: an experimental study†

Author(s) -

I. Yu. Zhuravleva,

N. R. Nichay,

Yu.Yu. Kulyabin,

T.P. Timchenko,

Aleksandr A. Korobeinikov,

Yuliya F. Polienko,

S. S. Shatskaya,

Elena V. Kuznetsova,

A.V. Voitov,

Alexander BogachevProkophiev,

Alexander Karaskov

Publication year - 2017

Publication title -

interactive cardiovascular and thoracic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.546

H-Index - 56

eISSN - 1569-9293

pISSN - 1569-9285

DOI - 10.1093/icvts/ivx445

Subject(s) - medicine , von kossa stain , calcification , pericardium , glutaraldehyde , biomaterial , surgery , pathology , biomedical engineering , biochemistry , chemistry , alkaline phosphatase , enzyme

The development of calcification-resistant bioprosthetic materials is a very important challenge for paediatric surgery. The subcutaneous implantation in rats is the well-known first-stage model for this kind of research. Using this model, we aimed to compare calcification of the porcine aortic wall and bovine pericardium and jugular vein wall cross-linked with glutaraldehyde (GA) and ethylene glycol diglycidyl ether (DE). We also determined the efficacy of DE-preserved tissue modification with 2-(2-carboxyethylamino)ethylidene-1,1-bisphosphonic acid (CEABA).

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