Direct sternal administration of Vancomycin and Gentamicin during closure prevents wound infection† | Zendy

Martin Andreas | Zendy; Moritz Muckenhuber | Zendy; Doris Hutschala | Zendy; Alfred Kocher | Zendy; Florian Thalhammer | Zendy; Paul Vogt | Zendy; Tatjana Fleck | Zendy; Günther Laufer | Zendy

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Direct sternal administration of Vancomycin and Gentamicin during closure prevents wound infection†

Author(s) -

Martin Andreas,

Moritz Muckenhuber,

Doris Hutschala,

Alfred Kocher,

Florian Thalhammer,

Paul Vogt,

Tatjana Fleck,

Günther Laufer

Publication year - 2017

Publication title -

interactive cardiovascular and thoracic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.546

H-Index - 56

eISSN - 1569-9293

pISSN - 1569-9285

DOI - 10.1093/icvts/ivx032

Subject(s) - medicine , perioperative , gentamicin , surgery , antibiotics , antibiotic prophylaxis , vancomycin , anesthesia , randomized controlled trial , methicillin resistant staphylococcus aureus , staphylococcus aureus , genetics , bacteria , microbiology and biotechnology , biology

Deep sternal wound infection is still a major complication in patients undergoing cardiac surgery. We previously identified mammary artery harvesting as a risk factor for decreased antibiotic tissue penetration. In addition, other risk factors including diabetes may inhibit sufficient tissue penetration of perioperative antibiotic prophylaxis. A novel closure protocol applying 2 topical antibiotics and further recommendations for sternal wiring was introduced at our department to decrease the incidence of sternal wound infections.

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