The role of myocardial ischaemic preconditioning during beating heart surgery: biological aspect and clinical outcome | Zendy

Efstratios Apostolakis | Zendy; Nikolaos G. Baikoussis | Zendy; Nikolaos A. Papakonstantinou | Zendy

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The role of myocardial ischaemic preconditioning during beating heart surgery: biological aspect and clinical outcome

Author(s) -

Efstratios Apostolakis,

Nikolaos G. Baikoussis,

Nikolaos A. Papakonstantinou

Publication year - 2011

Publication title -

interactive cardiovascular and thoracic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.546

H-Index - 56

eISSN - 1569-9293

pISSN - 1569-9285

DOI - 10.1093/icvts/ivr024

Subject(s) - medicine , cardiology , myocardial infarction , ischemic preconditioning , ischemia , angina , artery , coronary artery occlusion , bypass grafting

Short periods of ischaemia consecutive to reperfusion periods before a sustained ischaemic condition, the so-called ischaemic preconditioning (IP), aim to protect myocardial cells against prolonged ischaemia. IP appears as a considerable endogenous cardioprotective mechanism decreasing the infarct size after total occlusion in either experimental models or humans. Angina periods before an acute coronary syndrome limit the myocardial infarction being protective for the myocardium. Our report aims to review the international bibliography of the IP during off-pump coronary artery bypass grafting.

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