Salvage debulking surgery and hyperthermic intrathoracic chemotherapy for massive recurrent mesothelioma in the mediastinum | Zendy

Shi Sum Poon | Zendy; Fortunata Caterina Alberti | Zendy; Marco Nardini | Zendy; Marcello Migliore | Zendy

Open Access

Salvage debulking surgery and hyperthermic intrathoracic chemotherapy for massive recurrent mesothelioma in the mediastinum

Author(s) -

Shi Sum Poon,

Fortunata Caterina Alberti,

Marco Nardini,

Marcello Migliore

Publication year - 2022

Publication title -

interactive cardiovascular and thoracic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.546

H-Index - 56

eISSN - 1569-9293

pISSN - 1569-9285

DOI - 10.1093/icvts/ivac034

Subject(s) - medicine , decortication , debulking , pleurectomy , mesothelioma , surgery , mediastinum , extrapleural pneumonectomy , tamponade , radiology , pneumonectomy , peritoneal mesothelioma , lung , cancer , pathology , ovarian cancer

Mediastinal malignant pleural mesothelioma with signs of tamponade is rare. Indication for reoperation for recurrent malignant pleural mesothelioma is a controversial but viable option in selected patients. We report a case of a 68-year-old man presenting with epithelioid malignant pleural mesothelioma who underwent a total of three debulking surgeries (pleurectomy/decortication) combined with hyperthermic intrathoracic chemotherapy. Five years after the first procedure, a third urgent operation was performed for recurrence of a large mediastinal mesothelioma causing acute symptoms of pericardial constriction and tamponade. The patient was alive for eight years since the first treatment and 36 months after the second reoperation.

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