Host resource supplies influence the dynamics and outcome of infectious disease
Author(s) -
Val H. Smith
Publication year - 2007
Publication title -
integrative and comparative biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.328
H-Index - 123
eISSN - 1557-7023
pISSN - 1540-7063
DOI - 10.1093/icb/icm006
Subject(s) - host (biology) , biology , organism , limiting , resource (disambiguation) , competition (biology) , ecology , infectious disease (medical specialty) , ecosystem , disease , medicine , mechanical engineering , paleontology , computer network , pathology , computer science , engineering
Pathogens and their host organisms share a wide range of resource needs that are required to support normal metabolism and growth. Because the development of infectious disease on or within the host involves the processes of invasion and resource consumption, competition for growth-limiting resources potentially may occur between pathogens and cellular or sub-cellular components of the host ecosystem. Examples from the plant, animal, and microbiological literature provide unambiguous evidence that external resource supplies to the host organism can have profound effects on the outcome of infection by a broad diversity of bacterial, fungal, metazoan, protozoan, and viral pathogens.
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