Differential Expression of Soluble Receptor for Advanced Glycation End-products in Mice Susceptible or Resistant to Chronic Colitis
Author(s) -
Michael Bramhall,
Kevin Rich,
Ajanta Chakraborty,
Larisa Logunova,
Namshik Han,
James L. Wilson,
John McLaughlin,
Andy Brass,
Sheena M. Cruickshank
Publication year - 2019
Publication title -
inflammatory bowel diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.932
H-Index - 146
eISSN - 1536-4844
pISSN - 1078-0998
DOI - 10.1093/ibd/izz311
Subject(s) - colitis , medicine , rage (emotion) , inflammation , glycation , ulcerative colitis , immunology , immune system , inflammatory bowel disease , receptor , dysbiosis , disease , biology , gut flora , neuroscience
Identifying the factors that contribute to chronicity in inflamed colitic tissue is not trivial. However, in mouse models of colitis, we can investigate at preclinical timepoints. We sought to validate murine Trichuris muris infection as a model for identification of factors that promote development of chronic colitis.
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