Infliximab and Adalimumab Concentrations May Vary Between the Enzyme-Linked Immunosorbent Assay and the Homogeneous Mobility Shift Assay in Patients With Inflammatory Bowel Disease: A Prospective Cross-Sectional Observational Study
Author(s) -
William T. Clarke,
Konstantinos Papamichael,
Niels Vande Casteele,
Katharine A. Germansky,
Joseph D. Feuerstein,
Gil Y. Melmed,
Corey A. Siegel,
Peter M. Irving,
Adam S. Cheifetz
Publication year - 2019
Publication title -
inflammatory bowel diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.932
H-Index - 146
eISSN - 1536-4844
pISSN - 1078-0998
DOI - 10.1093/ibd/izz202
Subject(s) - medicine , infliximab , adalimumab , observational study , inflammatory bowel disease , prospective cohort study , homogeneous , gastroenterology , cross sectional study , disease , pathology , physics , thermodynamics
This prospective observational study including consecutive patients with inflammatory bowel disease treated with either infliximab or adalimumab showed that although the correlation between the ELISA and the homogeneous mobility shift assay was good for both drugs, the agreement was poor.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom