Untargeted Metabolomics and Inflammatory Markers Profiling in Children With Crohn’s Disease and Ulcerative Colitis—A Preliminary Study | Zendy

Urszula Daniluk | Zendy; Jarosław Daniluk | Zendy; Rafal Kucharski | Zendy; Tomasz Kowalczyk | Zendy; Karolina Pietrowska | Zendy; Paulina Samczuk | Zendy; Aleksandra Filimoniuk | Zendy; Adam Krętowski | Zendy; Dariusz Lebensztejn | Zendy; Michał Ciborowski | Zendy

Open Access

Untargeted Metabolomics and Inflammatory Markers Profiling in Children With Crohn’s Disease and Ulcerative Colitis—A Preliminary Study

Author(s) -

Urszula Daniluk,

Jarosław Daniluk,

Rafal Kucharski,

Tomasz Kowalczyk,

Karolina Pietrowska,

Paulina Samczuk,

Aleksandra Filimoniuk,

Adam Krętowski,

Dariusz Lebensztejn,

Michał Ciborowski

Publication year - 2019

Publication title -

inflammatory bowel diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.932

H-Index - 146

eISSN - 1536-4844

pISSN - 1078-0998

DOI - 10.1093/ibd/izy402

Subject(s) - ulcerative colitis , inflammatory bowel disease , crohn's disease , medicine , metabolomics , disease , profiling (computer programming) , crohn disease , immunology , bioinformatics , biology , computer science , operating system

Metabolic profiling might be used to identify disease biomarkers. The aim of our study was to determine the usefulness of untargeted metabolomics analysis to detect differences in serum metabolites between newly diagnosed and untreated pediatric patients with Crohn's disease (CD) or ulcerative colitis (UC) in comparison with a control group (Ctr). Moreover, we investigated the potential of profiling metabolomics and inflammatory markers to improve the noninvasive diagnosis of CD and UC in children.

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