Adverse Reactions After Intravenous Iron Infusion Among Inflammatory Bowel Disease Patients in the United States, 2010–2014 | Zendy

Eboselume Akhuemonkhan | Zendy; Alyssa Parian | Zendy; Kathryn A. Carson | Zendy; Susan Hutfless | Zendy

Open Access

Adverse Reactions After Intravenous Iron Infusion Among Inflammatory Bowel Disease Patients in the United States, 2010–2014

Author(s) -

Eboselume Akhuemonkhan,

Alyssa Parian,

Kathryn A. Carson,

Susan Hutfless

Publication year - 2018

Publication title -

inflammatory bowel diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.932

H-Index - 146

eISSN - 1536-4844

pISSN - 1078-0998

DOI - 10.1093/ibd/izy063

Subject(s) - medicine , ferumoxytol , iron sucrose , inflammatory bowel disease , adverse effect , anemia , gastroenterology , ulcerative colitis , iron deficiency anemia , iron deficiency , intravenous iron , disease , magnetic resonance imaging , radiology

Anemia is a frequent complication of Crohn's disease (CD) and ulcerative colitis (UC), collectively known as inflammatory bowel disease (IBD). Intravenous (IV) iron is recommended as the initial therapy for patients with clinically active IBD, severe anemia, and intolerance to oral iron. IV iron is associated with serious adverse effects including a black box warning for anaphylaxis with iron dextran and ferumoxytol. We aimed to examine the occurrence of adverse reactions including anaphylaxis after IV iron infusions in a large database of US IBD patients.

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