Free and Bioavailable 25-Hydroxyvitamin D Concentrations are Associated With Disease Activity in Pediatric Patients With Newly Diagnosed Treatment Naïve Ulcerative Colitis | Zendy

Cary G. Sauer | Zendy; Matthew Shane Loop | Zendy; Suresh Venkateswaran | Zendy; Vin Tangpricha | Zendy; Thomas R. Ziegler | Zendy; Ashish Dhawan | Zendy; Courtney McCall | Zendy; Erin Bonkowski | Zendy; David Mack | Zendy; Brendan Boyle | Zendy; Anne M. Griffiths | Zendy; Neal S. LeLeiko | Zendy; David J. Keljo | Zendy; James Markowitz | Zendy; Susan S. Baker | Zendy; Joel R. Rosh | Zendy; Robert N. Baldassano | Zendy; Sonia M. Davis | Zendy; Shiven B. Patel | Zendy; Jessie Wang | Zendy; Alison Marquis | Zendy; Krista Spada | Zendy; Subra Kugathasan | Zendy; Thomas D. Walters | Zendy; Jeffrey S. Hyams | Zendy; Lee A. Denson | Zendy

Open Access

Free and Bioavailable 25-Hydroxyvitamin D Concentrations are Associated With Disease Activity in Pediatric Patients With Newly Diagnosed Treatment Naïve Ulcerative Colitis

Author(s) -

Cary G. Sauer,

Matthew Shane Loop,

Suresh Venkateswaran,

Vin Tangpricha,

Thomas R. Ziegler,

Ashish Dhawan,

Courtney McCall,

Erin Bonkowski,

David Mack,

Brendan Boyle,

Anne M. Griffiths,

Neal S. LeLeiko,

David J. Keljo,

James Markowitz,

Susan S. Baker,

Joel R. Rosh,

Robert N. Baldassano,

Sonia M. Davis,

Shiven B. Patel,

Jessie Wang,

Alison Marquis,

Krista Spada,

Subra Kugathasan,

Thomas D. Walters,

Jeffrey S. Hyams,

Lee A. Denson

Publication year - 2018

Publication title -

inflammatory bowel diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.932

H-Index - 146

eISSN - 1536-4844

pISSN - 1078-0998

DOI - 10.1093/ibd/izx052

Subject(s) - medicine , ulcerative colitis , vitamin d and neurology , calprotectin , gastroenterology , inflammatory bowel disease , bioavailability , vitamin d deficiency , disease , pharmacology

Vitamin D regulates intestinal epithelial and immune functions, and vitamin D receptor deficiency increases the severity of murine colitis. Bioavailable 25-hydroxyvitamin D (25(OH)D) is available to target tissues and may be a driver of immune function. The aim is to evaluate the relationship of bioavailable 25(OH)D to the clinical expression of treatment naive pediatric ulcerative colitis (UC).

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