Genomic Landscape of Early-stage Colorectal Neoplasia Developing From the Ulcerative Colitis Mucosa in the Japanese Population | Zendy

Kenta Matsumoto | Zendy; Yuji Urabe | Zendy; Shiro Oka | Zendy; Katsuaki Inagaki | Zendy; Hidenori Tanaka | Zendy; Ryo Yuge | Zendy; Ryohei Hayashi | Zendy; Yasuhiko Kitadai | Zendy; Koji Arihiro | Zendy; Fumio Shimamoto | Zendy; Shinji Tanaka | Zendy; Kazuaki Chayama | Zendy

Open Access

Genomic Landscape of Early-stage Colorectal Neoplasia Developing From the Ulcerative Colitis Mucosa in the Japanese Population

Author(s) -

Kenta Matsumoto,

Yuji Urabe,

Shiro Oka,

Katsuaki Inagaki,

Hidenori Tanaka,

Ryo Yuge,

Ryohei Hayashi,

Yasuhiko Kitadai,

Koji Arihiro,

Fumio Shimamoto,

Shinji Tanaka,

Kazuaki Chayama

Publication year - 2020

Publication title -

inflammatory bowel diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.932

H-Index - 146

eISSN - 1536-4844

pISSN - 1078-0998

DOI - 10.1093/ibd/izaa268

Subject(s) - kras , ulcerative colitis , colorectal cancer , dysplasia , medicine , cancer research , cancer , disease

Colorectal neoplasias (CRN)s developing from the ulcerative colitis (UC) mucosa include both colitic and sporadic neoplasias. Although several genomic analyses of advanced colitis-associated cancer are available, such studies do not distinguish between colitic and sporadic cases, and the early-stage genomic alterations involved in the onset of colitic cancer remain unclear. To address this, we performed a genomic analysis of early-stage CRN developing from the UC mucosa (CRNUC).

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