From gametogenesis and stem cells to cancer: common metabolic themes | Zendy

Sandro L. Pereira | Zendy; Ana Sofia Rodrigues | Zendy; Maria Inês Sousa | Zendy; Marcelo Correia | Zendy; Tânia Perestrelo | Zendy; João RamalhoSantos | Zendy

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From gametogenesis and stem cells to cancer: common metabolic themes

Author(s) -

Sandro L. Pereira,

Ana Sofia Rodrigues,

Maria Inês Sousa,

Marcelo Correia,

Tânia Perestrelo,

João RamalhoSantos

Publication year - 2014

Publication title -

human reproduction update

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.977

H-Index - 180

eISSN - 1362-4946

pISSN - 1355-4786

DOI - 10.1093/humupd/dmu034

Subject(s) - stem cell , biology , cancer stem cell , induced pluripotent stem cell , cancer cell , microbiology and biotechnology , cancer , cancer research , cellular differentiation , bioinformatics , genetics , embryonic stem cell , gene

Both pluripotent stem cells (PSCs) and cancer cells have been described as having similar metabolic pathways, most notably a penchant for favoring glycolysis even under aerobiosis, suggesting common themes that might be explored for both stem cell differentiation and anti-oncogenic purposes.

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