A critical assessment of the endocrine susceptibility of the human testis to phthalates from fetal life to adulthood | Zendy

Océane Albert | Zendy; Bernard Jégou | Zendy

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A critical assessment of the endocrine susceptibility of the human testis to phthalates from fetal life to adulthood

Author(s) -

Océane Albert,

Bernard Jégou

Publication year - 2013

Publication title -

human reproduction update

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.977

H-Index - 180

eISSN - 1362-4946

pISSN - 1355-4786

DOI - 10.1093/humupd/dmt050

Subject(s) - endocrine system , disorders of sex development , fetus , human life , endocrinology , medicine , human health , human studies , physiology , pregnancy , hormone , biology , environmental health , philosophy , humanity , theology , genetics

A very large proportion of the literature on the endocrine disruptors categorized as anti-androgens deals with phthalates, which are produced in large amounts for use as plastic emollients and additives. In this review, we bring together and analyse work on the effects of phthalates in animals and humans at different stages of their development to assess whether or not their possible anti-androgenic properties represent a significant threat to human health.

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