The combined human sperm proteome: cellular pathways and implications for basic and clinical science | Zendy

Alexandra Amaral | Zendy; Judit Castillo | Zendy; João RamalhoSantos | Zendy; Rafael Oliva | Zendy

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The combined human sperm proteome: cellular pathways and implications for basic and clinical science

Author(s) -

Alexandra Amaral,

Judit Castillo,

João RamalhoSantos,

Rafael Oliva

Publication year - 2013

Publication title -

human reproduction update

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.977

H-Index - 180

eISSN - 1362-4946

pISSN - 1355-4786

DOI - 10.1093/humupd/dmt046

Subject(s) - proteomics , proteome , biology , sperm , gamete , microbiology and biotechnology , computational biology , bioinformatics , genetics , gene

The human sperm cell is very well suited for proteomic studies, as it is accessible, can be easily purified and is believed to be transcriptionally and translationally silent. The recent use of advanced proteomic approaches is clearly challenging the understanding of sperm biology. The aims of this review are to discuss the various human sperm proteomic studies, to create a compiled list of all the sperm proteins described to date and to re-assess the potential functional implications.

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