Genetic variants and the risk of gestational diabetes mellitus: a systematic review
Author(s) -
Cuilin Zhang,
Wei Bao,
Rong Ying,
Huixia Yang,
Katherine Bowers,
Edwina Yeung,
Michele Kiely
Publication year - 2013
Publication title -
human reproduction update
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.977
H-Index - 180
eISSN - 1362-4946
pISSN - 1355-4786
DOI - 10.1093/humupd/dmt013
Subject(s) - gestational diabetes , single nucleotide polymorphism , diabetes mellitus , genetic association , medicine , genome wide association study , bioinformatics , pregnancy , genetics , obstetrics , biology , endocrinology , gestation , genotype , gene
Several studies have examined associations between genetic variants and the risk of gestational diabetes mellitus (GDM). However, inferences from these studies were often hindered by limited statistical power and conflicting results. We aimed to systematically review and quantitatively summarize the association of commonly studied single nucleotide polymorphisms (SNPs) with GDM risk and to identify important gaps that remain for consideration in future studies.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom