Open AccessEndometriosis: hormone regulation and clinical consequences of chemotaxis and apoptosis
Author(s) -
Fernando M. Reis,
Felice Petraglia,
Robert N. Taylor
Publication year - 2013
Publication title -
human reproduction update
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.977
H-Index - 180
eISSN - 1362-4946
pISSN - 1355-4786
DOI - 10.1093/humupd/dmt010
Subject(s) - paracrine signalling , endometriosis , hormone , chemokine , endocrine system , apoptosis , immune system , endometrium , biology , chemotaxis , medicine , immunology , cancer research , endocrinology , receptor , biochemistry
The recruitment of immune cells by chemokines and the regulation of endometrial cell apoptosis are critical aspects of endometriosis biology. Here, we review the local (paracrine) and systemic hormone (endocrine) modulation of these two specific, but highly related phenomena.
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