Dynamics and ethics of comprehensive preimplantation genetic testing: a review of the challenges | Zendy

Kristien Hens | Zendy; Wybo Dondorp | Zendy; Alan H. Handyside | Zendy; Joyce Harper | Zendy; Ainsley J. Newson | Zendy; Guido Pennings | Zendy; Christoph RehmannSutter | Zendy; G. de Wert | Zendy

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Dynamics and ethics of comprehensive preimplantation genetic testing: a review of the challenges

Author(s) -

Kristien Hens,

Wybo Dondorp,

Alan H. Handyside,

Joyce Harper,

Ainsley J. Newson,

Guido Pennings,

Christoph RehmannSutter,

G. de Wert

Publication year - 2013

Publication title -

human reproduction update

Language(s) - English

Resource type - Journals

eISSN - 1362-4946

pISSN - 1355-4786

DOI - 10.1093/humupd/dmt009

Subject(s) - genetic testing , preimplantation genetic diagnosis , engineering ethics , biology , computational biology , genetics , engineering , pregnancy

Genetic testing of preimplantation embryos has been used for preimplantation genetic diagnosis (PGD) and preimplantation genetic screening (PGS). Microarray technology is being introduced in both these contexts, and whole genome sequencing of blastomeres is also expeted to become possible soon. The amount of extra information such tests will yield may prove to be beneficial for embryo selection, will also raise various ethical issues. We present an overview of the developments and an agenda-setting exploration of the ethical issues.

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