Noninvasive detection of fetal trisomy 21: systematic review and report of quality and outcomes of diagnostic accuracy studies performed between 1997 and 2012 | Zendy

Elke Mersy | Zendy; Luc Smits | Zendy; L.A.A.P. van Winden | Zendy; Christine de DieSmulders | Zendy; Aimée Paulussen | Zendy; Merryn Macville | Zendy; A. Coumans | Zendy; Suzanna G.M. Frints | Zendy

Open Access

Noninvasive detection of fetal trisomy 21: systematic review and report of quality and outcomes of diagnostic accuracy studies performed between 1997 and 2012

Author(s) -

Elke Mersy,

Luc Smits,

L.A.A.P. van Winden,

Christine de DieSmulders,

Aimée Paulussen,

Merryn Macville,

A. Coumans,

Suzanna G.M. Frints

Publication year - 2013

Publication title -

human reproduction update

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.977

H-Index - 180

eISSN - 1362-4946

pISSN - 1355-4786

DOI - 10.1093/humupd/dmt001

Subject(s) - trisomy , confidence interval , medicine , meta analysis , prenatal diagnosis , obstetrics , pathology , fetus , pregnancy , genetics , biology

Research on noninvasive prenatal testing (NIPT) of fetal trisomy 21 is developing fast. Commercial tests have become available. To provide an up-to-date overview of NIPT of trisomy 21, an evaluation of the methodological quality and outcomes of diagnostic accuracy studies was made.

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