The vascular endothelial growth factor family in adverse pregnancy outcomes | Zendy

Prabha H. Andraweera | Zendy; Gustaaf Dekker | Zendy; Claire T. Roberts | Zendy

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The vascular endothelial growth factor family in adverse pregnancy outcomes

Author(s) -

Prabha H. Andraweera,

Gustaaf Dekker,

Claire T. Roberts

Publication year - 2012

Publication title -

human reproduction update

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.977

H-Index - 180

eISSN - 1362-4946

pISSN - 1355-4786

DOI - 10.1093/humupd/dms011

Subject(s) - placental growth factor , placentation , vascular endothelial growth factor , soluble fms like tyrosine kinase 1 , pregnancy , medicine , intrauterine growth restriction , recurrent miscarriage , miscarriage , preeclampsia , obstetrics , placenta , angiogenesis , small for gestational age , gestation , bioinformatics , fetus , biology , vegf receptors , genetics

Pre-eclampsia, small-for-gestational-age infants, preterm birth and recurrent miscarriage complicate a significant number of pregnancies. The vascular endothelial growth factor (VEGF) family of angiogenic growth factors is implicated in the pathophysiology of these complications. We aimed to elucidate the role of these angiogenic factors in placentation and to evaluate the predictive value of their protein concentrations and genetic variations in pregnancy complications.

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