Genetic predictors of controlled ovarian hyperstimulation: where do we stand today? | Zendy

Signe Altmäe | Zendy; Outi Hovatta | Zendy; Anneli StavreusEvers | Zendy; Andres Salumets | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Genetic predictors of controlled ovarian hyperstimulation: where do we stand today?

Author(s) -

Signe Altmäe,

Outi Hovatta,

Anneli StavreusEvers,

Andres Salumets

Publication year - 2011

Publication title -

human reproduction update

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.977

H-Index - 180

eISSN - 1362-4946

pISSN - 1355-4786

DOI - 10.1093/humupd/dmr034

Subject(s) - controlled ovarian hyperstimulation , ovarian reserve , oncology , folliculogenesis , medicine , bioinformatics , pharmacogenetics , gynecology , infertility , cochrane library , biology , endocrinology , genetics , meta analysis , pregnancy , gene , genotype , lactation

Nowadays, the use of IVF has improved the prospects of infertility treatment. The expected outcome of IVF depends greatly on the effectiveness of controlled ovarian hyperstimulation (COH), where exogenous gonadotrophins are used to induce folliculogenesis. The response to stimulation varies substantially among women and is difficult to predict. Several predictive markers of COH outcome have been proposed (e.g. maternal age and ovarian reserve), but the search for optimal predictors is ongoing. Pharmacogenetic studies demonstrate the effects of individual genetic variability on COH outcome and the potential for customizing therapy based on the patient's genome.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research