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Epidemiology of Chlamydia trachomatis infection in women and the cost-effectiveness of screening
Author(s) -
J. A. Land,
Jan van Bergen,
Servaas A. Morré,
Maarten J. Postma
Publication year - 2009
Publication title -
human reproduction update
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.977
H-Index - 180
eISSN - 1362-4946
pISSN - 1355-4786
DOI - 10.1093/humupd/dmp035
Subject(s) - pelvic inflammatory disease , chlamydia trachomatis , chlamydia , infertility , tubal factor infertility , cervicitis , medicine , gynecology , asymptomatic , population , epidemiology , obstetrics , immunology , biology , pregnancy , environmental health , genetics
The majority of Chlamydia trachomatis infections in women are asymptomatic, but may give rise to pelvic inflammatory disease (PID) and tubal infertility. Screening programmes aim at reducing morbidity in individuals by early detection and treatment, and at decreasing the overall prevalence of infection in the population. A number of modelling studies have tried to calculate the threshold prevalence of chlamydia lower genital tract infection above which screening becomes cost-effective. There is considerable debate over the exact complication rates after chlamydia infections, and more precise estimates of PID and tubal infertility are needed, for instance to be inserted in economic models.

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