Male infertility and the involvement of the X chromosome | Zendy

Katrien Stouffs | Zendy; Herman Tournaye | Zendy; I. Liebaers | Zendy; Willy Lissens | Zendy

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Male infertility and the involvement of the X chromosome

Author(s) -

Katrien Stouffs,

Herman Tournaye,

I. Liebaers,

Willy Lissens

Publication year - 2009

Publication title -

human reproduction update

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.977

H-Index - 180

eISSN - 1362-4946

pISSN - 1355-4786

DOI - 10.1093/humupd/dmp023

Subject(s) - male infertility , biology , genetics , infertility , gene , y chromosome , x chromosome , spermatogenesis , chromosome , pregnancy , endocrinology

Male infertility is a worldwide problem, keeping many researchers puzzled. Besides environmental factors, much attention is paid to single gene defects. In this view, the sex chromosomes are particularly interesting since men only have a single copy of these chromosomes. The involvement of the Y chromosome in male infertility is obvious since the detection of Yq microdeletions. The role of the X chromosome, however, remains less understood.

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