Adiponectin levels in women with polycystic ovary syndrome: a systematic review and a meta-analysis | Zendy

Konstantinos A. Toulis | Zendy; Dimitrios G. Goulis | Zendy; Dimitrios Farmakiotis | Zendy; Neoklis A. Georgopoulos | Zendy; Ilias Katsikis | Zendy; Basil C. Tarlatzis | Zendy; Ioannis Papadimas | Zendy; Dimitrios Panidis | Zendy

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Adiponectin levels in women with polycystic ovary syndrome: a systematic review and a meta-analysis

Author(s) -

Konstantinos A. Toulis,

Dimitrios G. Goulis,

Dimitrios Farmakiotis,

Neoklis A. Georgopoulos,

Ilias Katsikis,

Basil C. Tarlatzis,

Ioannis Papadimas,

Dimitrios Panidis

Publication year - 2009

Publication title -

human reproduction update

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.977

H-Index - 180

eISSN - 1362-4946

pISSN - 1355-4786

DOI - 10.1093/humupd/dmp006

Subject(s) - adiponectin , polycystic ovary , medicine , meta analysis , insulin resistance , body mass index , endocrinology , obesity , testosterone (patch)

Conflicting results regarding adiponectin levels in women with polycystic ovary syndrome (PCOS) have been reported. To evaluate adiponectin levels in PCOS, a systematic review of all studies comparing adiponectin levels in women with PCOS with healthy controls and a meta-analysis of those involving women with similar body mass index (BMI) were performed. The influence of possible effect modifiers, such as insulin resistance (IR) and testosterone, was investigated. The influence of obesity was investigated through a 'nested' meta-analysis after within-study BMI stratification and appropriate pooling.

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