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Ovarian tissue cryopreservation and transplantation: a review
Author(s) -
Jacques Donnez,
Belén Martínez-Madrid,
Pascale Jadoul,
Anne Van Langendonckt,
Dominique Demylle,
MarieMadeleine Dolmans
Publication year - 2006
Publication title -
human reproduction update
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.977
H-Index - 180
eISSN - 1362-4946
pISSN - 1355-4786
DOI - 10.1093/humupd/dml032
Subject(s) - fertility preservation , oocyte cryopreservation , ovarian tissue cryopreservation , cryopreservation , embryo cryopreservation , transplantation , premature ovarian failure , medicine , fertility , gynecology , radiation therapy , premature ovarian insufficiency , oncology , biology , embryo , population , environmental health , microbiology and biotechnology
The review covers current options for ovarian tissue cryopreservation and transplantation and provides a systematic review of the existing literature from the last 10 years, taking into account all previously published reviews on the subject. The different cryopreservation options available for fertility preservation in cancer patients are embryo cryopreservation, oocyte cryopreservation and ovarian tissue cryopreservation. The choice depends on various parameters: the type and timing of chemotherapy, the type of cancer, the patient's age and the partner status. The different options and their results are discussed, as well as their putative indications and efficacy. The review concludes that advances in reproductive technology have made fertility preservation techniques a real possibility for patients whose gonadal function is threatened by premature menopause, or by treatments such as radiotherapy, chemotherapy or surgical castration.

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