Combined noninvasive metabolic and spindle imaging as potential tools for embryo and oocyte assessment
Author(s) -
Tim Sanchez,
Marta Venturas,
S. Ali Aghvami,
Xingbo Yang,
Seth Fraden,
Denny Sakkas,
Daniel Needleman
Publication year - 2019
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/dez210
Subject(s) - nicotinamide adenine dinucleotide , blastocyst , embryo , biology , flavin adenine dinucleotide , fluorescence lifetime imaging microscopy , oocyte , autofluorescence , embryogenesis , biochemistry , microbiology and biotechnology , nad+ kinase , enzyme , fluorescence , cofactor , physics , quantum mechanics
Supported by the Blavatnik Biomedical Accelerator Grant at Harvard University and by the Harvard Catalyst/The Harvard Clinical and Translational Science Center (National Institutes of Health Award UL1 TR001102), by NSF grants DMR-0820484 and PFI-TT-1827309 and by NIH grant R01HD092550-01. T.S. was supported by a National Science Foundation Postdoctoral Research Fellowship in Biology grant (1308878). S.F. and S.A. were supported by NSF MRSEC DMR-1420382. Becker and Hickl GmbH sponsored the research with the loaning of equipment for FLIM. T.S. and D.N. are cofounders and shareholders of LuminOva, Inc., and co-hold patents (US20150346100A1 and US20170039415A1) for metabolic imaging methods. D.S. is on the scientific advisory board for Cooper Surgical and has stock options with LuminOva, Inc.
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