Dysregulation of FGFR signalling by a selective inhibitor reduces germ cell survival in human fetal gonads of both sexes and alters the somatic niche in fetal testes | Zendy

Katrine Harpelunde Poulsen | Zendy; Jens Høiriis Nielsen | Zendy; Hanne Frederiksen | Zendy; Cecilie Melau | Zendy; Kristine Juul Hare | Zendy; Lea Langhoff Thuesen | Zendy; Signe Perlman | Zendy; Lene Lundvall | Zendy; Rod T. Mitchell | Zendy; Anders Juul | Zendy; Ewa RajpertDe Meyts | Zendy; Anne Jørgensen | Zendy

Open Access

Dysregulation of FGFR signalling by a selective inhibitor reduces germ cell survival in human fetal gonads of both sexes and alters the somatic niche in fetal testes

Author(s) -

Katrine Harpelunde Poulsen,

Jens Høiriis Nielsen,

Hanne Frederiksen,

Cecilie Melau,

Kristine Juul Hare,

Lea Langhoff Thuesen,

Signe Perlman,

Lene Lundvall,

Rod T. Mitchell,

Anders Juul,

Ewa RajpertDe Meyts,

Anne Jørgensen

Publication year - 2019

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dez191

Subject(s) - gonocyte , biology , fgf9 , somatic cell , germ cell , wnt4 , endocrinology , medicine , sertoli cell , fibroblast growth factor , ovary , microbiology and biotechnology , andrology , spermatogenesis , signal transduction , receptor , genetics , wnt signaling pathway , gene

Does experimental manipulation of fibroblast growth factor 9 (FGF9)-signalling in human fetal gonads alter sex-specific gonadal differentiation?

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