Open AccessDefining the limits of detection for chromosome rearrangements in the preimplantation embryo using next generation sequencing
Author(s) -
Carly Cuman,
Claire E. Beyer,
D. Brodie,
Tod Fullston,
Jane I. Lin,
Elissa Willats,
Deirdre ZanderFox,
J. A. Mullen
Publication year - 2018
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/dey227
Subject(s) - biology , comparative genomic hybridization , chromosomal inversion , chromosome , genetics , chromosomal rearrangement , dna sequencing , computational biology , karyotype , dna , gene
Is next generation sequencing (NGS) capable of detecting smaller sub-chromosomal rearrangements in human embryos than the manufacturer's quoted resolution suggests?
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