Chromosomal mosaicism in human blastocysts: the ultimate challenge of preimplantation genetic testing?
Author(s) -
Mina Popovic,
Annelies Dheedene,
Christina Christodoulou,
Jasin Taelman,
Lien Dhaenens,
Filip Van Nieuwerburgh,
Dieter Deforce,
E. Van den Abbeel,
Petra De Sutter,
Björn Menten,
Björn Heindryckx
Publication year - 2018
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/dey106
Subject(s) - inner cell mass , embryo , biology , concordance , preimplantation genetic diagnosis , andrology , aneuploidy , blastocyst , blastomere , genetics , biopsy , genetic testing , gynecology , embryogenesis , chromosome , pathology , medicine , gene
To what extent does a trophectoderm (TE) biopsy reliably reflect the chromosomal constitution of the inner cell mass (ICM) in human blastocysts?
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