Open AccessCreatine enhances the duration of sperm capacitation: a novel factor for improving in vitro fertilization with small numbers of sperm
Author(s) -
Takashi Umehara,
Tomoko Kawai,
Masaaki Goto,
JoAnne S. Richards,
Masayuki Shimada
Publication year - 2018
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/dey081
Subject(s) - capacitation , sperm , human fertilization , andrology , ovulation , oocyte , in vitro fertilisation , creatine , biology , sperm motility , in vivo , endocrinology , medicine , embryo , anatomy , hormone , microbiology and biotechnology , genetics
Why are many sperm required for successful fertilization of oocytes in vitro, even though fertilization occurs in vivo when only a few sperm reach the oocyte?
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