In vitro differentiation of human oocyte-like cells from oogonial stem cells: single-cell isolation and molecular characterization
Author(s) -
Erica Silvestris,
Paola Cafforio,
Stella D’Oronzo,
Claudia Felici,
Franco Silvestris,
Giuseppe Loverro
Publication year - 2017
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/dex377
Subject(s) - biology , oocyte , stem cell , oogenesis , cellular differentiation , ovarian cortex , meiosis , in vitro maturation , microbiology and biotechnology , ovary , andrology , endocrinology , genetics , embryo , medicine , ovarian tissue , gene
Are the large cells derived from cultured DEAD box polypeptide 4 (DDX4)-positive oogonial stem cells (OSCs), isolated from the ovarian cortex of non-menopausal and menopausal women, oocyte-like cells?
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