Open AccessMAEL promoter hypermethylation is associated with de-repression of LINE-1 in human hypospermatogenesis
Author(s) -
YuSheng Cheng,
Shi-Kae Wee,
Tsung-Yen Lin,
Yung-Ming Lin
Publication year - 2017
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/dex329
Subject(s) - dna methylation , psychological repression , biology , methylation , transposable element , microbiology and biotechnology , genetics , gene , gene expression , mutant
Does the hypermethylation of the maelstrom spermatogenic transposon silencer (MAEL) promoter and subsequent de-repression of transposable elements represent one of the causes of spermatogenic failure in infertile men?
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom