Targeted metabolomics reveals reduced levels of polyunsaturated choline plasmalogens and a smaller dimethylarginine/arginine ratio in the follicular fluid of patients with a diminished ovarian reserve
Author(s) -
Juan Manuel Chao de la Barca,
Thomas Boueilh,
Gilles Simard,
Lisa Boucret,
Véronique Ferré-L’Hôtellier,
Laure Tessier,
Cédric Gadras,
PierreEmmanuel Bouet,
Philippe Descamps,
Vincent Procaccio,
Pascal Reynier,
Pascale MayPanloup
Publication year - 2017
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/dex303
Subject(s) - metabolomics , follicular fluid , ovarian reserve , biology , context (archaeology) , medicine , in vitro fertilisation , oocyte , andrology , univariate analysis , metabolite , endocrinology , physiology , pregnancy , infertility , multivariate analysis , bioinformatics , embryo , genetics , paleontology
Does the metabolomic profile of the follicular fluid (FF) of patients with a diminished ovarian reserve (DOR) differ from that of patients with a normal ovarian reserve (NOR)?
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