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The production of glial cell line-derived neurotrophic factor by human sertoli cells is substantially reduced in sertoli cell-only testes
Author(s) -
Dolly Singh,
Darius A. Paduch,
Peter N. Schlegel,
Kyle E. Orwig,
Anna Mielnik,
Alexander Bolyakov,
William W. Wright
Publication year - 2017
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/dex061
Subject(s) - sertoli cell , microbiology and biotechnology , cell culture , biology , neurotrophic factors , medicine , endocrinology , spermatogenesis , genetics , receptor
Do human Sertoli cells in testes that exhibit the Sertoli cell-only (SCO) phenotype produce substantially less glial cell line-derived neurotrophic factor (GDNF) than Sertoli cells in normal testes?

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