Preserved seminiferous tubule integrity with spermatogonial survival and induction of Sertoli and Leydig cell maturation after long-term organotypic culture of prepubertal human testicular tissue
Author(s) -
Francesca de Michele,
Jonathan Poels,
L. Weerens,
Céline Petit,
Z. Evrard,
Jérôme Ambroise,
Damien Gruson,
Christine Wyns
Publication year - 2016
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/dew300
Subject(s) - biology , sertoli cell , seminiferous tubule , andrology , leydig cell , spermatogenesis , organ culture , endocrinology , medicine , testosterone (patch) , luteinizing hormone , hormone , in vitro , biochemistry
Is an organotypic culture system able to provide the appropriate testicular microenvironment for in-vitro maturation of human immature testicular tissue (ITT)?
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom