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Preserved seminiferous tubule integrity with spermatogonial survival and induction of Sertoli and Leydig cell maturation after long-term organotypic culture of prepubertal human testicular tissue
Author(s) -
Francesca de Michele,
Jonathan Poels,
L. Weerens,
Céline Petit,
Z. Evrard,
Jérôme Ambroise,
Damien Gruson,
Christine Wyns
Publication year - 2016
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/dew300
Subject(s) - biology , sertoli cell , seminiferous tubule , andrology , leydig cell , spermatogenesis , organ culture , endocrinology , medicine , testosterone (patch) , luteinizing hormone , hormone , in vitro , biochemistry
Is an organotypic culture system able to provide the appropriate testicular microenvironment for in-vitro maturation of human immature testicular tissue (ITT)?

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