Open AccessDevelopment and characterization of a novel long-acting recombinant follicle stimulating hormone agonist by fusing Fc to an FSH-β subunit
Author(s) -
Yinli Zhang,
Kang-Ping Guo,
ShuYan Ji,
Xiaoman Liu,
Pilin Wang,
Jie Wu,
Li Gao,
Tianqi Jiang,
Ting Xu,
HengYu Fan
Publication year - 2015
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/dev295
Subject(s) - recombinant dna , follicle stimulating hormone , agonist , endocrinology , medicine , protein subunit , chemistry , biology , andrology , hormone , receptor , luteinizing hormone , biochemistry , gene
Does a novel long-acting recombinant human FSH, KN015, a heterodimer composed of FSHα and FSHβ-Fc/Fc, offer a potential FSH alternative?
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