Open AccessHuman embryos commonly form abnormal nuclei during development: a mechanism of DNA damage, embryonic aneuploidy, and developmental arrest
Author(s) -
Daniel H. Kort,
Gloryn Chia,
Nathan R. Treff,
Akemi Tanaka,
Tongji Xing,
Lauren Bauer,
Stephanie Micucci,
Robert Prosser,
Roger A. Lobo,
Mark V. Sauer,
Dieter Egli
Publication year - 2015
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/dev281
Subject(s) - aneuploidy , embryo , mechanism (biology) , biology , dna damage , embryonic stem cell , embryogenesis , genetics , microbiology and biotechnology , andrology , dna , medicine , chromosome , gene , philosophy , epistemology
What is the prevalence and developmental significance of morphologic nuclear abnormalities in human preimplantation embryos?
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