The magnitude of gonadotoxicity of chemotherapy drugs on ovarian follicles and granulosa cells varies depending upon the category of the drugs and the type of granulosa cells
Author(s) -
Aytaç Yüksel,
Gamze Bildik,
Filiz Senbabaoglu,
Nazlı Akin,
Macit Arvas,
Fehmi Ünal,
Yagmur Kilic,
Işıl Karanfil,
Baldan Eryılmaz,
Pelin Yilmaz,
Can Ozkanbaş,
Çağatay Taşkıran,
Senai Aksoy,
Yılmaz Güzel,
Başak Balaban,
Ümit İnce,
Akira Iwase,
Bülent Urman,
Özgür Öktem
Publication year - 2015
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/dev256
Subject(s) - ovary , follicle , in vivo , ovarian follicle , granulosa cell , biology , medicine , mitosis , in vitro , chemotherapy , endocrinology , andrology , microbiology and biotechnology , genetics
Do different chemotherapy drugs exert the same magnitude of cytotoxicity on dormant primordial follicles and the growing follicle fraction in the ovary in vivo and on mitotic non-luteinized and non-mitotic luteinized granulosa cells in vitro?
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