Chromosome segregation regulation in human zygotes: altered mitotic histone phosphorylation dynamics underlying centromeric targeting of the chromosomal passenger complex | Zendy

C. van de Werken | Zendy; Margarida Avo Santos | Zendy; Joop S.E. Laven | Zendy; C. Eleveld | Zendy; Bart C.J.M. Fauser | Zendy; Susanne M.A. Lens | Zendy; Esther B. Baart | Zendy

Open Access

Chromosome segregation regulation in human zygotes: altered mitotic histone phosphorylation dynamics underlying centromeric targeting of the chromosomal passenger complex

Author(s) -

C. van de Werken,

Margarida Avo Santos,

Joop S.E. Laven,

C. Eleveld,

Bart C.J.M. Fauser,

Susanne M.A. Lens,

Esther B. Baart

Publication year - 2015

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dev186

Subject(s) - biology , microbiology and biotechnology , histone h3 , metaphase , mitosis , prometaphase , zygote , histone , centromere , aurora b kinase , chromosome segregation , phosphorylation , kinetochore , genetics , chromosome , embryo , gene , embryogenesis

Are the kinase feedback loops that regulate activation and centromeric targeting of the chromosomal passenger complex (CPC), functional during mitosis in human embryos?

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