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Enough! Stop the arguments and get on with the science of natural killer cell testing
Author(s) -
Gavin Sacks
Publication year - 2015
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/dev096
Subject(s) - natural killer cell , immune system , medicine , immunology , empirical research , intensive care medicine , natural (archaeology) , bioinformatics , biology , epistemology , cytotoxicity , paleontology , biochemistry , philosophy , in vitro
Natural killer cell testing is currently practised widely, and there are studies indicating potential benefit in terms of targeting women with repeated reproductive failure for immune therapy. This may be a better approach than empirical immune therapy without any investigation. More and better studies are needed before such an approach can be fully endorsed. There is still uncertainty over the precise pathophysiological basis for all immune investigation and therapy, but this should not be a barrier for clinical observation and empirical care. On the contrary, clinicians and researchers should work more closely together to provide the best care for our patients.

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