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Human cumulus-enclosed germinal vesicle oocytes from early antral follicles reveal heterogeneous cellular and molecular features associated with in vitro maturation capacity
Author(s) -
F. Guerrero Sánchez,
Sergio Romero,
Michel De Vos,
Greta Verheyen,
Johan Smitz
Publication year - 2015
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/dev083
Subject(s) - germinal vesicle , oocyte , in vitro maturation , andrology , antral follicle , biology , meiosis , polycystic ovary , ovarian follicle , microbiology and biotechnology , ovary , embryo , endocrinology , genetics , medicine , insulin resistance , insulin , gene
Are oocyte size, chromatin remodelling, transcriptional activity and mitochondrial distribution in human immature oocytes from early antral follicles retrieved for in vitro maturation (IVM) associated with the acquisition of meiotic competence?

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