Application of next-generation sequencing technology for comprehensive aneuploidy screening of blastocysts in clinical preimplantation genetic screening cycles
Author(s) -
Francesco Fiorentino,
Sara Bono,
Anıl Biricik,
Andrea Nuccitelli,
Ettore Cotroneo,
Giuliano Cottone,
Felix Kokocinski,
Claude-Edouard Michel,
Maria Giulia Minasi,
Ermanno Greco
Publication year - 2014
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/deu277
Subject(s) - aneuploidy , comparative genomic hybridization , biology , genetic testing , blastocyst , embryo transfer , embryo , preimplantation genetic diagnosis , microarray , advanced maternal age , fluorescence in situ hybridization , genetics , andrology , bioinformatics , genome , medicine , fetus , pregnancy , gene , embryogenesis , chromosome , gene expression
Can next-generation sequencing (NGS) techniques be used reliably for comprehensive aneuploidy screening of human embryos from patients undergoing IVF treatments, with the purpose of identifying and selecting chromosomally normal embryos for transfer?
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