Clinically relevant enhancement of human sperm motility using compounds with reported phosphodiesterase inhibitor activity | Zendy

Steve Tardif | Zendy; Oladipo A. Madamidola | Zendy; Sean G. Brown | Zendy; L Frame | Zendy; Linda Lefièvre | Zendy; Paul G. Wyatt | Zendy; Christopher L. R. Barratt | Zendy; Sarah Martins da Silva | Zendy

Open Access

Clinically relevant enhancement of human sperm motility using compounds with reported phosphodiesterase inhibitor activity

Author(s) -

Steve Tardif,

Oladipo A. Madamidola,

Sean G. Brown,

L Frame,

Linda Lefièvre,

Paul G. Wyatt,

Christopher L. R. Barratt,

Sarah Martins da Silva

Publication year - 2014

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deu196

Subject(s) - sperm motility , motility , sperm , phosphodiesterase , phosphodiesterase inhibitor , andrology , chemistry , pharmacology , medicine , biology , enzyme , microbiology and biotechnology , biochemistry

Can we identify compound(s) with reported phosphodiesterase inhibitor (PDEI) activity that could be added to human spermatozoa in vitro to enhance their motility without compromising other sperm functions?

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