Expression patterns of DLK1 and INSL3 identify stages of Leydig cell differentiation during normal development and in testicular pathologies, including testicular cancer and Klinefelter syndrome | Zendy

Grete Lottrup | Zendy; Jens Høiriis Nielsen | Zendy; Lisa Leth Maroun | Zendy; Lars Mikael Alling Møller | Zendy; Musaab Yassin | Zendy; Henrik Leffers | Zendy; Niels E. Skakkebæk | Zendy; Ewa RajpertDe Meyts | Zendy

Open Access

Expression patterns of DLK1 and INSL3 identify stages of Leydig cell differentiation during normal development and in testicular pathologies, including testicular cancer and Klinefelter syndrome

Author(s) -

Grete Lottrup,

Jens Høiriis Nielsen,

Lisa Leth Maroun,

Lars Mikael Alling Møller,

Musaab Yassin,

Henrik Leffers,

Niels E. Skakkebæk,

Ewa RajpertDe Meyts

Publication year - 2014

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deu124

Subject(s) - biology , klinefelter syndrome , endocrinology , leydig cell , sexual differentiation , medicine , male infertility , andrology , cellular differentiation , infertility , hormone , luteinizing hormone , genetics , gene , pregnancy

What is the differentiation stage of human testicular interstitial cells, in particular Leydig cells (LC), within micronodules found in patients with infertility, testicular cancer and Klinefelter syndrome?

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