Hyperglycaemic conditions perturb mouse oocyte in vitro developmental competence via beta-O-linked glycosylation of Heat shock protein 90 | Zendy

Laura A. Frank | Zendy; Melanie L. SuttonMcDowall | Zendy; Hannah M. Brown | Zendy; Darryl L. Russell | Zendy; Robert B. Gilchrist | Zendy; Jeremy G. Thompson | Zendy

Open Access

Hyperglycaemic conditions perturb mouse oocyte in vitro developmental competence via beta-O-linked glycosylation of Heat shock protein 90

Author(s) -

Laura A. Frank,

Melanie L. SuttonMcDowall,

Hannah M. Brown,

Darryl L. Russell,

Robert B. Gilchrist,

Jeremy G. Thompson

Publication year - 2014

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deu066

Subject(s) - western blot , biology , heat shock protein , oocyte , embryo , immunocytochemistry , medicine , immunoprecipitation , andrology , endocrinology , glycosylation , blot , embryogenesis , hsp90 , hsp70 , microbiology and biotechnology , biochemistry , immunology , antibody , gene

What is the effect of beta-O-linked glycosylation (O-GlcNAcylation) on specific proteins in the cumulus-oocyte complex (COC) under hyperglycaemic conditions?

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