Environmental toxicants perturb human Sertoli cell adhesive function via changes in F-actin organization mediated by actin regulatory proteins | Zendy

Xiang Xiao | Zendy; D Mruk | Zendy; Elizabeth I. Tang | Zendy; Chris K.C. Wong | Zendy; WeiMing Lee | Zendy; Constance M. John | Zendy; P. J. Turek | Zendy; Bruno Silvestrini | Zendy; C. Yan Cheng | Zendy

Open Access

Environmental toxicants perturb human Sertoli cell adhesive function via changes in F-actin organization mediated by actin regulatory proteins

Author(s) -

Xiang Xiao,

D Mruk,

Elizabeth I. Tang,

Chris K.C. Wong,

WeiMing Lee,

Constance M. John,

P. J. Turek,

Bruno Silvestrini,

C. Yan Cheng

Publication year - 2014

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deu011

Subject(s) - sertoli cell , microbiology and biotechnology , blood–testis barrier , cadmium chloride , toxicant , biology , in vitro , reproductive toxicity , chemistry , spermatogenesis , andrology , toxicity , endocrinology , cadmium , biochemistry , medicine , organic chemistry

Can human Sertoli cells cultured in vitro and that have formed an epithelium be used as a model to monitor toxicant-induced junction disruption and to better understand the mechanism(s) by which toxicants disrupt cell adhesion at the Sertoli cell blood-testis barrier (BTB)?

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