Enhanced generation of human embryonic stem cells from single blastomeres of fair and poor-quality cleavage embryos via inhibition of glycogen synthase kinase β and Rho-associated kinase signaling
Author(s) -
Adeleh Taei,
SeyedehNafiseh Hassani,
Poopak EftekhariYazdi,
Mojtaba Rezazadeh Valojerdi,
Mohsen Nokhbatolfoghahai,
Najmehsadat Masoudi,
Mohammad Pakzad,
Hamid Gourabi,
Hossein Baharvand
Publication year - 2013
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/det309
Subject(s) - embryonic stem cell , blastomere , embryo , gsk 3 , biology , microbiology and biotechnology , cleavage (geology) , blastocyst , stem cell , inner cell mass , embryogenesis , kinase , genetics , paleontology , fracture (geology) , gene
Could selected pluripotency-enhancing small molecules (SMs) lead to efficient derivation of human embryonic stem cells (hESCs) from cleavage embryos-derived single blastomeres (SBs)?
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