Single-nucleotide polymorphism microarray-based preimplantation genetic diagnosis is likely to improve the clinical outcome for translocation carriers | Zendy

YueQiu Tan | Zendy; Ke Tan | Zendy; S.- P. Zhang | Zendy; Fei Gong | Zendy; Dehua Cheng | Zendy; Bo Xiong | Zendy; CanZhong Lu | Zendy; Xiaoning Tang | Zendy; K Luo | Zendy; Ge Lin | Zendy; G. X. Lu | Zendy

Open Access

Single-nucleotide polymorphism microarray-based preimplantation genetic diagnosis is likely to improve the clinical outcome for translocation carriers

Author(s) -

YueQiu Tan,

Ke Tan,

S.- P. Zhang,

Fei Gong,

Dehua Cheng,

Bo Xiong,

CanZhong Lu,

Xiaoning Tang,

K Luo,

Ge Lin,

G. X. Lu

Publication year - 2013

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/det271

Subject(s) - preimplantation genetic diagnosis , chromosomal translocation , single nucleotide polymorphism , biology , blastomere , snp array , snp , embryo , embryo transfer , fluorescence in situ hybridization , genetics , microarray , biopsy , andrology , gene , genotype , medicine , pathology , embryogenesis , gene expression , chromosome

Is preimplantation genetic diagnosis (PGD) for translocation carriers more effective when done with a single-nucleotide polymorphism (SNP) array using trophectoderm (TE) biopsy and frozen embryo transfer (FET) compared with traditional PGD based on fluorescence in situ hybridization (FISH-PGD) using blastomere biopsy and fresh embryo transfer?

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