Session 25: ASRM exchange session - Genetic and metabolic consequences for fertility in men and women

terms of live birth rate, nor the safety for the resulting children is evaluated properly. Whether the reported cardio-metabolic effects in IVF children can, just as in animals, be attributed to culture medium is not known either. Although much more knowledge on this topic is needed, current reported culture effects cannot be neglected anymore. Together with the manufacturers the current pre-implementation tests for newly developed culture media or for new additives should be reconsidered. In the IVF centres we should become more critical on which culture medium to use and evaluate the success rate by properly designed randomized controlled trials (RCTs), preferably in multiple centres in different countries. More importantly, a consistent follow-up of health parameters in the IVF children resulting from these RCTs is necessary to reveal culture medium induced health effects in human.